AlphaPulldown
Description
AlphaPulldown, a Python package that streamlines protein-protein interaction screens and high-throughput modelling of higher-order oligomers using AlphaFold-Multimer. It provides a convenient command line interface, a variety of confidence scores, and a graphical analysis tool.
Environment Modules
Run module spider alphapulldown to find out what environment modules are available for this application.
System Variables
- HPC_ALPHAPULLDOWN_DIR - installation directory
- HPC_ALPHAPULLDOWN_BIN - executable directory
Citation
If you use this software, please cite it along the dependencies it uses internally, at least:
Yu,D. et al. (2022) AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer. Bioinformatics, Volume 39, Issue 1, January 2023, btac749
Jumper,J. et al. (2021) Highly accurate protein structure prediction with AlphaFold. Nature 2021 596:7873, 596, 583–589.
Evans,R. et al. (2022) Protein complex prediction with AlphaFold-Multimer.