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AlphaPulldown website  

AlphaPulldown, a Python package that streamlines protein-protein interaction screens and high-throughput modelling of higher-order oligomers using AlphaFold-Multimer. It provides a convenient command line interface, a variety of confidence scores, and a graphical analysis tool.

Environment Modules

Run module spider alphapulldown to find out what environment modules are available for this application.

System Variables

  • HPC_ALPHAPULLDOWN_DIR - installation directory
  • HPC_ALPHAPULLDOWN_BIN - executable directory


If you use this software, please cite it along the dependencies it uses internally, at least:

Yu,D. et al. (2022) AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer. Bioinformatics, Volume 39, Issue 1, January 2023, btac749

Jumper,J. et al. (2021) Highly accurate protein structure prediction with AlphaFold. Nature 2021 596:7873, 596, 583–589.

Evans,R. et al. (2022) Protein complex prediction with AlphaFold-Multimer.