Difference between revisions of "XWAS"
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− | + | [https://academic.oup.com/jhered/article/106/5/666/2960036 Gao F, Chang D, Biddanda A, Ma L, Guo Y, Zhou Z, Keinan A. "XWAS: a toolset for genetic data analysis and association studies of the X chromosome." Journal of Heredity. 2015;106(5):6.] | |
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Latest revision as of 13:27, 31 August 2020
Description
The X chromosome plays an important role in complex human traits and diseases, especially those with sexually dimorphic characteristics. Special attention needs to be given to the analysis of X due to its unique inheritance pattern and X-inactivation. These analytical complications have resulted in exclusion or mishandling of the X chromosome in the majority of genome-wide association studies (GWAS) to date. With XWAS, we hope to provide the tools and incentive to accurately incorporate the X chromosome into GWAS, hence enabling discoveries of novel loci implicated in many diseases and in their sexual dimorphism.
Environment Modules
Run module spider xwas
to find out what environment modules are available for this application.
System Variables
- HPC_XWAS_DIR - installation directory
- HPC_XWAS_BIN - executable directory
- HPC_XWAS_DOC - documentation directory
- HPC_XWAS_EXE - example directory
Citation
If you publish research that uses xwas you have to cite it as follows: