Liner mixed models are widely used in genetics. One of the fundamental assumptions of these models-that the data have a particular distribution (i.e., the noise is Gaussian-distributed)-rarely holds in practice. As a result, standard approaches yield sub-optimal performance, resulting in significant losses in power for GWAS, increased bias in heritability estimation, and reduced accuracy for phenotype predictions.
module spider WarpedLMM to find out what environment modules are available for this application.
- HPC_WARPEDLMM_DIR - installation directory