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syri website  

SyRI is a comprehensive tool for predicting genomic differences between related genomes using whole-genome assemblies (WGA). The assemblies are aligned using whole-genome alignment tools, and these alignments are then used as input to SyRI. SyRI identifies syntenic path (longest set of co-linear regions), structural rearrangements (inversions, translocations, and duplications), local variations (SNPs, indels, CNVs etc) within syntenic and structural rearrangements, and un-aligned regions.

Environment Modules

Run module spider syri to find out what environment modules are available for this application.

System Variables

  • HPC_SYRI_DIR - installation directory
  • HPC_SYRI_BIN - executable directory


If you publish research that uses syri you have to cite it as follows:

Goel, M., Sun, H., Jiao, W. et al. SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies. Genome Biol 20, 277 (2019) doi:10.1186/s13059-019-1911-0