This software package is for estimating allele and genotype frequencies from nucleotide read quartets (read counts of A, C, G, and T) derived from individual high-throughput sequencing data for multiple diploid individuals from a population by a maximum-likelihood (ML) method.
- HPC_PACKAGE-GFE_DIR - installation directory
If you publish research that uses package-gfe you have to cite it as follows:
Maruki, T., and Lynch, M., (2015) Genotype-frequency estimation from high-throughput sequencing data. Genetics (in press).