P53MH

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Description

p53mh website  

Computes a score between 0 and 100 for each site in the DNA sequence of a gene. A high score indicates an increased probability that n nucleotides at that and subsequent sites represent a p53 binding site, where n = 2 x 10 + (selected length of spacer region).

Required Modules

Serial

  • p53mh

System Variables

  • HPC_P53MH_DIR - installation directory
  • HPC_P53MH_BIN - executable directory
  • HPC_P53MH_DAT - example data directory

Additional Information

p53MH requires a data file. You can copy the example data file to your current working directory with the follow command:

ml p53mh
cp $HPC_P53MH_DAT/* .



Citation

If you publish research that uses p53mh you have to cite it as follows:

Hoh J, Jin S, Parrado T, Edington J, Levine AJ, Ott J (2002) The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci USA 99, 8467-8472