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melting website  

MELTING is a software to compute, for a nucleic acid duplex, the enthalpy and the entropy of the helix coil transition and then the melting temperature. Four types of hybridization are possible : DNA/DNA, RNA/RNA, RNA/DNA and mRNA/RNA.

Environment Modules

Run module spider melting to find out what environment modules are available for this application.

System Variables

  • HPC_MELTING_DIR - installation directory


If you publish research that uses melting you have to cite it as follows:

Le Novère N. (2001). MELTING, computing the melting temperature of nucleic acid duplex. Bioinformatics, 17: 1226-1227.

Dumousseau M., Rodriguez N., Juty N., Le Novère N. (2012) MELTING, a flexible platform to predict the melting temperatures of nucleic acids. BMC Bioinformatics, 13: 101.