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GenomeScope2 website  

GenomeScope 2.0 applies classical insights from combinatorial theory to establish a detailed mathematical model of how k-mer frequencies will be distributed in heterozygous and polyploid genomes.

Environment Modules

Run module spider GenomeScope2 to find out what environment modules are available for this application.

System Variables

  • HPC_GENOMESCOPE2_DIR - installation directory
  • HPC_GENOMESCOPE2_BIN - executable directory


If you publish research that uses GenomeScope2 you have to cite it as follows:

Ranallo-Benavidez, T.R., Jaron, K.S. & Schatz, M.C. GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes. Nature Communications 11, 1432 (2020).

Vurture, GW, Sedlazeck, FJ, Nattestad, M, Underwood, CJ, Fang, H, Gurtowski, J, Schatz, MC (2017) Bioinformatics doi