Difference between revisions of "EvoLSTM"

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[[Category:Software]][[Category:Biology]][[Category::Bioinformatics]]
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{|<!--CONFIGURATION: REQUIRED-->
 
{|<!--CONFIGURATION: REQUIRED-->
 
|{{#vardefine:app|EvolSTM}}
 
|{{#vardefine:app|EvolSTM}}

Latest revision as of 18:52, 12 August 2022

Description

EvolSTM website  

A recurrent neural network-based evolution simulator that captures mutational context dependencies. EvoLSTM uses a sequence-to-sequence long short-term memory model trained to predict mutation probabilities at each position of a given sequence, taking into consideration the 14 flanking nucleotides. EvoLSTM can realistically simulate mammalian and plant DNA sequence evolution and reveals unexpectedly strong long-range context dependencies in mutation probabilities. EvoLSTM brings modern machine-learning approaches to bear on sequence evolution. It will serve as a useful tool to study and simulate complex mutational processes.

Environment Modules

Run module spider EvolSTM to find out what environment modules are available for this application.

System Variables

  • HPC_EVOLSTM_DIR - installation directory