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Canvas is a tool for calling copy number variants (CNVs) from human DNA sequencing data. It can work either with germline data, or paired tumor/normal samples. Its primary input is aligned reads (in .bam format), and its primary output is a report (in a .vcf file) giving the copy number status of the genome.

Environment Modules

Run module spider canvas to find out what environment modules are available for this application.

System Variables

  • HPC_CANVAS_DIR - installation directory
  • HPC_CANVAS_BIN - executable directory


If you publish research that uses canvas you have to cite it as follows:

Canvas was first described in the publication Canvas: versatile and scalable detection of copy number variants in the journal OUP Bioinformatics

The Canvas Small Pedigree Workflow was published in the journal OUP Bioinformatics: Canvas SPW: calling de novo copy number variants in pedigrees