INDELible
Description
INDELible is a new, portable, and flexible application for biological sequence simulation that combines many features in the same place for the first time. Using a length-dependent model of indel formation it can simulate evolution of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time.
Nucleotide simulations may use the general unrestricted model or the general time reversible model and its derivatives, and amino-acid simulations can be conducted using fifteen different empirical rate matrices. Substitution rate heterogeneity can be modelled via the continuous and discrete gamma distributions, with or without a proportion of invariant sites. INDELible can also simulate under non-homogenous and non-stationary conditions where evolutionary models are permitted to change across a phylogeny.
Environment Modules
Run module spider REPLACE to find out what environment modules are available for this application.
System Variables
- HPC_REPLACE_DIR - installation directory
- HPC_REPLACE_BIN - executable directory
Citation
If you publish research that uses REPLACE you have to cite it as follows: