Olego
Jump to navigation
Jump to search
Description
OLego is a program specifically designed for de novo spliced mapping of mRNA-seq reads. OLego adopts a seed-and-extend scheme, and does not rely on a separate external mapper. It achieves high sensitivity of junction detection by strategic searches with very small seeds (12-14 nt), efficiently mapped using Burrows-Wheeler transform (BWT) and FM-index. This also makes it particularly sensitive for discovering small exons. OLego supports multi-threading to allow for fast processing of large-scale data.
Required Modules
Serial
- olego
System Variables
- HPC_{{#uppercase:olego}}_DIR
Validation
- Validated 4/5/2018