SignalP

Description

signalp website  

SignalP 4.1 predicts the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes, and eukaryotes. The method incorporates a prediction of cleavage sites and a signal peptide/non-signal peptide prediction based on a combination of several artificial neural networks.

Required Modules

Serial

• signalp

System Variables

• HPC_{{#uppercase:signalp}}_DIR - installation directory

Additional Information

Note

On HiPerGator signalp code has been changed to create a temporary directory 'tmp' inside the current working directory to prevent signalp from filling up memory disks on HiPerGator2 diskless nodes. You will have to clean up the 'tmp' directory from the job directory after the job or as the last action in the job script to recover the space used by the analysis.

Citation

If you publish research that uses signalp you have to cite it as follows:

SignalP 4.0: discriminating signal peptides from transmembrane regions Thomas Nordahl Petersen, Søren Brunak, Gunnar von Heijne & Henrik Nielsen Nature Methods, 8:785-786, 2011