SIFT
Revision as of 17:22, 10 August 2012 by Moskalenko (talk | contribs) (Text replace - "<!--Run-->" to "==System Variables== * HPC_{{#uppercase:{{#var:app}}}}_DIR - installation directory <!--Run--> ")
Description
SIFT predicts whether an amino acid substitution affects protein function. SIFT prediction is based on the degree of conservation of amino acid residues in sequence alignments derived from closely related sequences, collected through PSI-BLAST. SIFT can be applied to naturally occurring nonsynonymous polymorphisms or laboratory-induced missense mutations.
Required Modules
Serial
- sift
System Variables
- HPC_{{#uppercase:sift}}_DIR - installation directory