USEARCH
Description
USEARCH is a unique high-throughput sequence analysis tool. It is a distributed as single binary program that implements a suite of algorithms comparable to BLASTN, BLASTP, BLASTX, BLASTCLUST, CD-HIT, CD-HIT-EST, CD-HIT-2D, CD-HIT-EST-2D, CD-HIT-OTU, CD-HIT-454, ChimeraSlayer, Perseus, RAPsearch and more. It supports a rich set of sequence matching options, including E-values, identity, coverage (fraction of query or target sequence covered by the alignment) and maximum gap length, and a range of output file formats including FASTA, BLAST-like, user-defined tabbed text and a native format designed for clustering applications. Supported alignment styles include local (gapped and ungapped), like BLAST, and global, which is most often used in clustering applications. User-settable parameters allow tuning of substitution scores, gap penalties and Karlin-Altschul statistics.
Required Modules
Serial
- usearch
System Variables
- HPC_USEARCH_DIR - installation directory
- HPC_USEARCH_BIN - executable directory
Usage Policy
We have a 64-bit licensed USEARCH binary in the usearch/7.0.1001-64 module.
Citation
If you publish research that uses usearch you have to cite it as follows:
Edgar, Robert C. - Search and clustering orders of magnitude faster than BLAST Bioinformatics, 2010 Author : Edgar, Robert C. Title : Search and clustering orders of magnitude faster than BLAST Publication : Bioinformatics Date : 2010
Validation
- Validated 4/5/2018