Difference between revisions of "MetaCluster"
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| − | MetaCluster is an unsupervised binning method for metagenomic sequences. Existing binning methods based on sequence similarity and sequence composition markers rely heavily on the reference genomes of known microorganisms and phylogenetic markers. MetaCluster is an integrated binning method based on the unsupervised top-down separation and bottom-up merging strategy. It can bin metagenomic sequencing datasets with mixed complex species abundance ratios from the exactly equal situation to the extremely unbalance situation with consistently higher accuracy | + | MetaCluster is an unsupervised binning method for metagenomic sequences. Existing binning methods based on sequence similarity and sequence composition markers rely heavily on the reference genomes of known microorganisms and phylogenetic markers. MetaCluster is an integrated binning method based on the unsupervised top-down separation and bottom-up merging strategy. It can bin metagenomic sequencing datasets with mixed complex species abundance ratios from the exactly equal situation to the extremely unbalance situation with consistently higher accuracy. |
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Revision as of 18:41, 15 November 2012
Description
metacluster website
MetaCluster is an unsupervised binning method for metagenomic sequences. Existing binning methods based on sequence similarity and sequence composition markers rely heavily on the reference genomes of known microorganisms and phylogenetic markers. MetaCluster is an integrated binning method based on the unsupervised top-down separation and bottom-up merging strategy. It can bin metagenomic sequencing datasets with mixed complex species abundance ratios from the exactly equal situation to the extremely unbalance situation with consistently higher accuracy.
Required Modules
Serial
- metacluster
System Variables
- HPC_{{#uppercase:metacluster}}_DIR - installation directory
- HPC_HTSEQ_BIN - executable directory.
Additional Information
Two programs are available - htseq-count and htseq-qa. Run them without any arguments to see the usage information. The main HTSeq module can be loaded from python (import HTSeq). See HTSeq documentation for a tutorial.