SIPeS: Difference between revisions
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==System Variables== | ==System Variables== | ||
* HPC_{{ | * HPC_{{uc:{{#var:app}}}}_DIR - installation directory | ||
<!--Configuration--> | <!--Configuration--> | ||
{{#if: {{#var: conf}}|==Configuration== | {{#if: {{#var: conf}}|==Configuration== | ||
Revision as of 21:24, 6 December 2019
Description
This module allows you to use SIPeS. With the advent of sequencing techniques, chromatin immunoprecipitation combined with high throughput sequencing (ChIP-Seq) is becoming a powerful tool to study protein-DNA interactions on genome-wide scale.SIPeS (Site Identification from Paired-end Sequencing), a novel algorithm, allows researchers to identify transcript factor binding sites from paired-end sequencing reads. SIPeS uses a dynamic baseline directly through the piling up of fragments to effectively find peaks, overcoming the disadvantage of estimating the average length of DNA fragments from singled-end sequencing achieving more powerful prediction binding sites with high sensitivity and specificity.
Required Modules
Serial
- sipes
System Variables
- HPC_SIPES_DIR - installation directory
Validation
- Validated 4/5/2018