Difference between revisions of "TRF"
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Revision as of 21:29, 6 December 2019
Description
A tandem repeat in DNA is two or more adjacent, approximate copies of a pattern of nucleotides. Tandem Repeats Finder is a program to locate and display tandem repeats in DNA sequences. In order to use the program, the user submits a sequence in FASTA format. There is no need to specify the pattern, the size of the pattern or any other parameter. The output consists of two files: a repeat table file and an alignment file. The repeat table contains information about each repeat, including its location, size, number of copies and nucleotide content. Clicking on the location indices for one of the table entries opens a second web browser that shows an alignment of the copies against a consensus pattern. The program is very fast, analyzing sequences on the order of .5Mb in just a few seconds. Submitted sequences may be of arbitrary length. Repeats with pattern size in the range from 1 to 2000 bases are detected. Sequence information sent to the server is confidential and deleted after program execution.
Required Modules
Serial
- trf
System Variables
- HPC_TRF_DIR - installation directory
Citation
If you publish research that uses trf you have to cite it as follows: G. Benson, "Tandem repeats finder: a program to analyze DNA sequences", Nucleic Acids Research (1999), Vol. 27, No. 2, pp. 573-580.
Validation
- Validated 4/5/2018