SIPeS

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Description

sipes website  

This module allows you to use SIPeS. With the advent of sequencing techniques, chromatin immunoprecipitation combined with high throughput sequencing (ChIP-Seq) is becoming a powerful tool to study protein-DNA interactions on genome-wide scale.SIPeS (Site Identification from Paired-end Sequencing), a novel algorithm, allows researchers to identify transcript factor binding sites from paired-end sequencing reads. SIPeS uses a dynamic baseline directly through the piling up of fragments to effectively find peaks, overcoming the disadvantage of estimating the average length of DNA fragments from singled-end sequencing achieving more powerful prediction binding sites with high sensitivity and specificity.

Required Modules

Serial

  • sipes

System Variables

  • HPC_SIPES_DIR - installation directory





Validation

  • Validated 4/5/2018