Difference between revisions of "SIFT"
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Revision as of 15:01, 5 April 2018
Description
SIFT predicts whether an amino acid substitution affects protein function. SIFT prediction is based on the degree of conservation of amino acid residues in sequence alignments derived from closely related sequences, collected through PSI-BLAST. SIFT can be applied to naturally occurring nonsynonymous polymorphisms or laboratory-induced missense mutations.
Required Modules
Serial
- sift
System Variables
- HPC_{{#uppercase:sift}}_DIR - installation directory
Validation
- Validated 4/5/2018