Parabricks is a software suite for genomic analysis. It delivers major improvements in throughput time for common analytical tasks in genomics, including germline and somatic analysis. The core of the Parabricks software is its data pipeline which takes raw data and transforms it according to the user's requirements.
module spider parabricks to find out what environment modules are available for this application.
- HPC_PARABRICKS_DIR - installation directory
- HPC_PARABRICKS_BIN - executable directory
An example job resource request based on the Nvidia recommendation:
srun -p gpu --constraint=rtx6000 -N 1 --cpus-per-task=16 --gpus=1 --mem=32gb --time=200:00 --pty bash -i
It is recommended to use the RTX6000 GPUs because the RTX 2080ti cards do no have enough memory. The '--num-gpus X' pbrun argument must match the number 'X' of requested GPUs. If not specified parabricks will try to run on all gpus on the compute node and exit with an error.
Note that a parabricks run may produce an error if the paths used as arguments for the run resolve to symlinks. Containerized tools need real paths i.e. use the /blue/mygroup/myuser/project/inputdir path instead of a shorter ~/blue/project/inputdir path that's using a symlink even if the ~/blue symlink is pointing to the /blue/mygroup/myuser/ directory./