Difference between revisions of "Minimac"

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* Validate 4/5/2018

Revision as of 21:22, 5 April 2018


minimac website  

Minimac is a low memory, computationally efficient implementation of the MaCH algorithm for genotype imputation. It is designed to work on phased genotypes and can handle very large reference panels with hundreds or thousands of haplotypes. The name has two parts. The first, "mini", refers to the modest amount of computational resources it requires. The second, "mac", is short hand for MaCH, our widely used algorithm for genotype imputation.

Required Modules


  • minimac

System Variables

  • HPC_{{#uppercase:minimac}}_DIR - installation directory


If you publish research that uses minimac you have to cite it as follows:

Fuchsberger C, Abecasis GR, Hinds DA. minimac2: faster genotype imputation. Bioinformatics 2014

Howie B, Fuchsberger C, Stephens M, Marchini J, and Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nature Genetics 2012.


  • Validate 4/5/2018