Difference between revisions of "Bwa-mem2"
(Created page with "Category:SoftwareCategory:Phylogenetics {|<!--CONFIGURATION: REQUIRED--> |{{#vardefine:app|Bwa-mem2}} |{{#vardefine:url|https://github.com/bwa-mem2/bwa-mem2}} <!--CONF...") |
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[[Category:Software]][[Category:Phylogenetics]] | [[Category:Software]][[Category:Phylogenetics]] | ||
{|<!--CONFIGURATION: REQUIRED--> | {|<!--CONFIGURATION: REQUIRED--> | ||
| − | |{{#vardefine:app| | + | |{{#vardefine:app|bwa-mem2}} |
|{{#vardefine:url|https://github.com/bwa-mem2/bwa-mem2}} | |{{#vardefine:url|https://github.com/bwa-mem2/bwa-mem2}} | ||
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|{{#vardefine:testing|}} <!--PROFILING--> | |{{#vardefine:testing|}} <!--PROFILING--> | ||
|{{#vardefine:faq|}} <!--FAQ--> | |{{#vardefine:faq|}} <!--FAQ--> | ||
| − | |{{#vardefine:citation|}} <!--CITATION--> | + | |{{#vardefine:citation|1}} <!--CITATION--> |
|{{#vardefine:installation|}} <!--INSTALLATION--> | |{{#vardefine:installation|}} <!--INSTALLATION--> | ||
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==System Variables== | ==System Variables== | ||
* HPC_{{uc:{{#var:app}}}}_DIR - installation directory | * HPC_{{uc:{{#var:app}}}}_DIR - installation directory | ||
| + | * HPC_{{uc:{{#var:app}}}}_BIN - executable directory | ||
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<!--Configuration--> | <!--Configuration--> | ||
{{#if: {{#var: conf}}|==Configuration== | {{#if: {{#var: conf}}|==Configuration== | ||
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If you publish research that uses {{#var:app}} you have to cite it as follows: | If you publish research that uses {{#var:app}} you have to cite it as follows: | ||
| − | + | Vasimuddin Md, Sanchit Misra, Heng Li, Srinivas Aluru. Efficient Architecture-Aware Acceleration of BWA-MEM for Multicore Systems. IEEE Parallel and Distributed Processing Symposium (IPDPS), 2019. | |
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|}} | |}} | ||
Latest revision as of 16:11, 27 May 2022
Description
We are happy to announce that the index size on disk is down by 8 times and in memory by 4 times due to moving to only one type of FM-index (2bit.64 instead of 2bit.64 and 8bit.32) and 8x compression of suffix array. For example, for human genome, index size on disk is down to ~10GB from ~80GB and memory footprint is down to ~10GB from ~40GB. There is a substantial reduction in index IO time due to the reduction and hardly any performance impact on read mapping. Due to this change in index structure (in commit #4b59796, 10th October 2020), you will need to rebuild the index.
Environment Modules
Run module spider bwa-mem2 to find out what environment modules are available for this application.
System Variables
- HPC_BWA-MEM2_DIR - installation directory
- HPC_BWA-MEM2_BIN - executable directory
Citation
If you publish research that uses bwa-mem2 you have to cite it as follows:
Vasimuddin Md, Sanchit Misra, Heng Li, Srinivas Aluru. Efficient Architecture-Aware Acceleration of BWA-MEM for Multicore Systems. IEEE Parallel and Distributed Processing Symposium (IPDPS), 2019.