Bsmap
Revision as of 21:19, 6 December 2019 by Moskalenko (talk | contribs) (Text replacement - "#uppercase" to "uc")
Description
BSMAP is a short reads mapping software for bisulfite sequencing reads. Bisulfite treatment converts unmethylated Cytosines into Uracils (sequenced as Thymine) and leave methylated Cytosines unchanged, hence provides a way to study DNA cytosine methylation at single nucleotide resolution. BSMAP aligns the Ts in the reads to both Cs and Ts in the reference.
Required Modules
Serial
- bsmap
System Variables
- HPC_BSMAP_DIR - installation directory
- HPC_BSMAP_DOC - documentation directory
Citation
If you publish research that uses bsmap you have to cite it as follows:
Xi Y, Li W: BSMAP: whole genome Bisulfite Sequence MAPping program. BMC Bioinformatics (2009) 10:232.
Validation
- Validated 4/5/2018