View source for SIFT

[[Category:Software]][[Category:Bioinformatics]][[Category:Genomics]]
{|<!--CONFIGURATION: REQUIRED-->
|{{#vardefine:app|sift}}
|{{#vardefine:url|http://sift.jcvi.org/}}
<!--CONFIGURATION: OPTIONAL (1=ON)-->
|{{#vardefine:mod|1}} <!--MODULES - NOW REQUIRED-->
|{{#vardefine:intel|}} <!-- "11.1" - Compiler Module Choice -->
|{{#vardefine:mpi|}} <!-- "openmpi/1.3.4"- MPI Module Choice -->
|{{#vardefine:exe|}} <!--RUNNING -->
|{{#vardefine:conf|}} <!--CONFIGS-->
|{{#vardefine:pbs|}} <!--PBS SCRIPTS-->
|{{#vardefine:policy|}} <!--POLICY-->
|{{#vardefine:testing|}} <!--TESTING/PROFILING-->
|{{#vardefine:faq|}} <!--FAQ-->
|{{#vardefine:citation|}} <!--CITATION-->
|{{#vardefine:installation|}} <!--INSTALLATION-->
|}
<!--BODY-->
<!--Description-->
{{#if: {{#var: url}}|
{{App_Description|app={{#var:app}}|url={{#var:url}}|name={{#var:app}}}}|}}

SIFT predicts whether an amino acid substitution affects protein function. SIFT prediction is based on the degree of conservation of amino acid residues in sequence alignments derived from closely related sequences, collected through PSI-BLAST. SIFT can be applied to naturally occurring nonsynonymous polymorphisms or laboratory-induced missense mutations. 
<!--Location-->
{{App_Location|app={{#var:app}}|{{#var:ver}}}}
<!--Versions-->
==Available versions==
* 4.0.3b
<!--Modules-->
{{#if: {{#var: mod}}|==Running the application using modules==
{{App_Module|app={{#var:app}}|intel={{#var:intel}}|mpi={{#var:mpi}}}}|}}
<!--Add additional HPC_FOO_BIN and other ENV VARIABLES below-->
<!--Run-->
{{#if: {{#var: exe}}|==How To Run==
DOUBLE_CLICK_TO_WRITE_INSTRUCTIONS_ON_RUNNING_THE_ACTUAL_BINARY
|}}
<!--Configuration-->
{{#if: {{#var: conf}}|==Configuration==
See the [[{{PAGENAME}}_Configuration]] page for {{#var: app}} configuration details.
|}}
<!--PBS scripts-->
{{#if: {{#var: pbs}}|==PBS Script Examples==
See the [[{{PAGENAME}}_PBS]] page for {{#var: app}} PBS script examples.|}}
<!--Policy-->
{{#if: {{#var: policy}}|==Usage policy==
WRITE USAGE POLICY HERE (perhaps templates for a couple of main licensing schemes can be used)
|}}
<!--Performance-->
{{#if: {{#var: testing}}|==Performance==
DOUBLE_CLICK_TO_WRITE_PERFORMANCE_TESTING_RESULTS_HERE
|}}
<!--Faq-->
{{#if: {{#var: faq}}|==FAQ==
*'''Q:''' **'''A:'''|}}
<!--Citation-->
{{#if: {{#var: citation}}|==Citation==
If you publish research that uses {{#var:app}} you have to cite it as follows:
DOUBLE_CLICK_TO_WRITE_CITATION_HERE
|}}
<!--Installation-->
{{#if: {{#var: installation}}|==Installation==
See the [[{{PAGENAME}}_Install]] page for {{#var: app}} installation notes.|}}
__NOTOC____NOEDITSECTION__