PolyPhen

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Description

polyphen website  

PolyPhen-2 (Polymorphism Phenotyping v2) is a software tool which predicts possible impact of amino acid substitutions on the structure and function of human proteins using straightforward physical and evolutionary comparative considerations.

Required Modules

Serial

  • polyphen

System Variables

  • HPC_POLYPHEN_DIR - installation directory




Citation

If you publish research that uses polyphen you have to cite it as follows:

Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Nat Methods 7(4):248-249 (2010).